W*ErgoteX (Vitamin D2) - MATERIAL SAFETY DATA SHEET

Product Name ERGOCALCIFEROL
Product Number E5750
Company identification: ”WIRUD” Co.Ltd
For emergencies, call: +86 (852) 2307 1788
+86 (852) 2307 1695

Substance Name :    CAS #
ERGOCALCIFEROL      50-14-6
Formula:         C28H44O
Synonyms:        D-Arthin * Calciferol * Calciferon 2 * Condacaps
* Condocaps * Condol * Crtron * Crystallina * Daral * Davitamon D * Davitin * Decaps * Dee-Osterol * Dee-Ron * Dee-Ronal * Dee-Roual * Deltalin * Deratol * Detalup * Diactol * Divit urto * Doral * Drisdol * Ergorone * Ergosterol activated * Ergosterol, irradiated * Ertron * Fortodyl * Geltabs * HI-Deratol * Hyperkil * Infron * Irradiated
ergosta-5,7, 22-trien-3-beta-ol * Metadee * Mulsiferol * Mykostin * Oleovitamin D * Ostelin * Rodinec * Radiostol * Radsterin * 9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10, (19),22 -tetraen-3-ol * Shock-ferol * Sorex C.R. * Sterogyl * Vigantol * Viosterol * Vitamin D2 * Vitavel-D RTECS Number:   KE1050000

EMERGENCY OVERVIEW
Highly Toxic (USA) Very Toxic (EU).
Toxic in contact with skin. Very toxic by inhalation and if swallowed. Toxic: danger of serious damage to health by prolonged exposure if swallowed.

ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.

INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

DERMAL EXPOSURE
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam.

FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Specific Hazard(s): Emits toxic fumes under fire conditions.

.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.

METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

HANDLING
User Exposure: Do not breathe dust. Do not get in eyes, on skin, on clothing. Avoid prolonged or repeated exposure.

ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.

PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Use respirators and components tested and approved under appropriate government standards such as

NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Hand: Compatible chemical-resistant gloves. Eye: Chemical safety goggles.

GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after handling.

Appearance : Physical State: Solid Color: White Form: Powder

Property: Value
Molecular Weight: 396.66 AMU
pH: N/A
BP/BP Range: N/A
MP/MP Range: 114 °C
Freezing Point: N/A
Vapor Pressure: N/A
Vapor Density: N/A
Saturated Vapor Cone.: N/A
SG/Density: N/A
Bulk Density: N/A
Odor Threshold: N/A
Volatile%: N/A
VOC Content: N/A
Water Content: N/A
Solvent Content: N/A
Evaporation Rate: N/A
Viscosity: N/A
Surface Tension: N/A
Partition Coefficient: N/A
Decomposition Temp.: N/A
Flash Point: N/A
Explosion Limits: N/A
Flammability: N/A

Refractive Index       N/A
Optical Rotation       Degree of Rotation: 40 g/1
Solvent: EtOH
+125 - +105 (+/-2)
Miscellaneous Data      N/A
Solubility            N/A

STABILITY
Stable: Stable.
Conditions of Instability: Air and light sensitive.
Materials to Avoid: Strong oxidizing agents, Strong acids, Strong bases.

HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide

ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: Toxic if absorbed through skin.
Eye Contact: May cause eye irritation.
Inhalation: May be fatal if inhaled. Material may be irritating
to mucous membranes and upper respiratory tract.
Ingestion: Toxic if swallowed.

SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

TOXICITY DATA
Oral
Rat
10 mg/kg
LD50
Oral Mouse
23.7 mg/kg LD50
Oral
Duck
> 2000 mg/kg
LD50

CHRONIC EXPOSURE - TERATOGEN
Species: Rat
Dose: 45 MG/KG
Route of Application: Oral
Exposure Time: (13-21D PREG)
Result: Specific Developmental Abnormalities: Endocrine system.
Species: Rat
Dose: 30 MG/KG
Route of Application: Oral
Exposure Time: (10-21D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death, e.g., stunted fetus).

Specific Developmental Abnormalities: Musculoskeletal system.
Effects on Newborn: Weaning or lactation index (e.g., # alive at weaning per # alive at day 4).
Species: Rat
Dose: 55 MG/KG
Route of Application: Oral
Exposure Time: (9-19D PREG)
Result: Specific Developmental Abnormalities: Musculoskeletal system.
Species: Rat Dose: 22500 UG/KG Route of Application: Oral Exposure Time: (13-21D PREG)
Result: Effects on Embryo or Fetus: Extra embryonic structures (e.g., placenta, umbilical cord). Effects on Newborn: Growth statistics (e.g., reduced weight gain).
Species: Rat Dose: 35 MG/KG
Route of Application: Intramuscular Exposure Time: (8-21D PREG)
Result: Effects on Newborn: Viability index (e.g., # alive at day 4 per # born alive). Effects on Newborn: Growth statistics (e.g., reduced weight gain). Specific Developmental Abnormalities: Musculoskeletal system.
Species: Mouse Dose: 200 MG/KG Route of Application: Oral Exposure Time: (4-7D PREG)
Result: Specific Developmental Abnormalities: Central nervous system. Specific Developmental Abnormalities: Craniofacial (including nose and tongue). Specific Developmental Abnormalities: Musculoskeletal system.
Species: Rabbit Dose: 1750 UG/KG
Route of Application: Intramuscular Exposure Time: (1-28D PREG)
Result: Specific Developmental Abnormalities: Cardiovascular (circulatory) system.

CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Result: Overexposure may cause reproductive disorder(s) based on tests with laboratory animals.
Species: Rat
Dose: 33750 UG/KG
Route of Application: Oral
Exposure Time: (9D PRE)
Result: Effects on Fertility: Female fertility index (e.g., #
females pregnant per # sperm positive females; # females
pregnant per # females mated ). Maternal Effects: Menstrual
cycle changes or disorders.
Species: Rat
Dose: 17500 UG/KG
Route of Application: Subcutaneous
Exposure Time: (1-7D PREG)
Result: Effects on Fertility: Female fertility index (e.g., #
females pregnant per # sperm positive females; # females pregnant per # females mated ).
Species: Rabbit
Dose: 9375 UG/KG
Route of Application: Intramuscular
Exposure Time: (2-31D PREG)
Result: Effects on Newborn: Delayed effects. Effects on Newborn: Weaning or lactation index (e.g., # alive at weaning per # alive at day 4). Effects on Newborn: Growth statistics (e.g., reduced weight gain).
Species: Rabbit
Dose: 17500 UG/KG
Route of Application: Intramuscular
Exposure Time: (1-28D PREG)
Result: Effects on Fertility: Abortion.

APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and local environmental regulations.

DOT
Proper Shipping Name: Toxic solids, organic, n.o.s.
UN#: 2811
Class: 6.1
Packing Group: Packing Group II
Hazard Label: Toxic substances.
PIH: Not PIH
IATA
Proper Shipping Name: Toxic solid, organic, n.o.s. IATA UN Number: 2 811 Hazard Class: 6.1 Packing Group: II

EU DIRECTIVES CLASSIFICATION Symbol of Danger: T+ Indication of Danger: Very toxic. R: 24/25-26-48/25
Risk Statements: Toxic in contact with skin and if swallowed. Very toxic by inhalation. Toxic: danger of serious damage to health by prolonged exposure if swallowed.
S: 28-36/37-45
Safety Statements: After contact with skin, wash immediately with plenty of soap and water. Wear suitable protective clothing and gloves. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Highly Toxic (USA) Very Toxic (EU). Risk Statements: Toxic in contact with skin. Very toxic by inhalation and if swallowed. Toxic: danger of serious damage to health by prolonged exposure if swallowed.
Safety Statements: After contact with skin, wash immediately with plenty of water. Wear suitable protective clothing and gloves. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in accordance with the hazard criteria of the CPR, and the MSDS contains all the information required by the CPR. DSL: Yes
NDSL: No